Expulsion and continuation rates between early and standard intrauterine contraception following medical management of first trimester incomplete abortions in central Uganda: a non-inferiority, open-label, randomised controlled trial

This parallel, non-inferiority, open-label, randomised controlled trial conducted in five public health facilities in central Uganda examined the expulsion and continuation rates of intrauterine devices (IUDs) following medical management of first trimester incomplete abortions. The study compared early insertion (within 1 week) versus standard insertion (2-4 weeks) timing in 1050 women aged 15 years or older. Results showed that early IUD insertion was non-inferior to standard insertion, with expulsion rates of 4% versus 5% respectively, and continuation rates of 91.1% versus 90.2% at 6 months. The most common safety event was post-abortion bleeding in approximately 30% of participants in both groups, with no serious adverse events occurring.